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Elizabeth Jacobs PhD

Elizabeth  Jacobs PhD

Professor

Epidemiology and Biostatistics Department

1515 N. Campbell
Campus PO Box: 245024
AZCC 4985
Tucson, AZ 85724
(520) 626-0341
jacobse@email.arizona.edu

Biography

Dr. Jacobs is a cancer and nutritional epidemiologist and Professor of Epidemiology and Biostatistics and Nutritional Sciences at the Mel and Enid Zuckerman College of Public Health and the University of Arizona Cancer Center.  She is currently the Principal Investigator of an R01 designed to investigate heterogeneity of treatment effect of selenium supplementation for chemoprevention.

Education:

2001, PhD, Nutritional Sciences, University of Arizona 

1996, MS, Foods and Nutrition, Purdue University 

Recent Publications:

Jacobs ET, Burgess JL, Abbott MB. The Donora Smog revisited: 70 Years after the event that inspired the Clean Air Act. Am J Public Health, 2018 Apr;108(S2):S85-S88. doi: 10.2105/AJPH.2017.304219.PMID: 29698099; PMCID:PMC5922205. 

Jacobs ET, Gupta S, Baron JA, Cross AJ, Lieberman DA, Murphy G, Martinez ME.  Family History of Colorectal Cancer in First-degree Relatives and Metachronous Colorectal Adenoma.Am J Gastroenterol. 2018 Feb 20. doi: 10.1038/s41395-018-0007-x. [Epub ahead of print]. PMID:29463834; PMC Journal; PMCID in progress. 

Jeong KS, Zhou J, Griffin S, Jacobs ET, Dearmon-Moore D, Littau SR, Gulotta J, Moore P, Peate W, Burgess JL. MicroRNA Changes in Firefighers. J Occup Environ Med,  2018 May; 60(5):469-474. doi: 10.1097/JOM.0000000000001307. PMID:29465512; PMC Journal; PMCID in progress.

Batai K,  Murphy AB, Ruden M, Newsome J, Shah E, Dixon MA, Jacobs ET, Hollowell CMP,  Ahaghotu C, Kittles RA. Race and BMI modify associations of calcium and vitamin D intake with prostate cancer. BMC Cancer. 2017 Jan 19; 17(1):64. doi: 10.1186/s12885-017-3060-8. PMID: 28103838; PMCID: PMC5248493.

Kohler LN, Hibler EA, Harris RB, Oren E, Roe DJ, Jurutka PW, Jacobs ET. Greater adherence to cancer prevention guidelines is associated with higher circulating concentrations of vitamin D metabolites in a cross-sectional analysis of pooled participants from two chemoprevention trials. J Nutr. 2017 Mar;147(3):421-429. doi: 10.3945/jn.116.243352. Epub 2017 Jan 25.PMID: 28122932. PMC Journal; PMCID in progress.

Lance P, Alberts DS, Thompson PA, Fales L, Wang F, San Jose J, Jacobs ET, Goodman PJ, Darke AK, Yee M, Minasian L, Thompson IM, Roe DJ. Colorectal Adenomas in Participants of the SELECT Trial of Selenium and Vitamin E for Prostate Cancer Prevention, Cancer Prev Res (Phila). 2017 Jan;10(1):45-54. doi: 10.1158/1940-6207.CAPR-16-0104. Epub 2016 Oct 24.PMID:27777235.

Sabir MS, Hu C, Khan Z, Galligan MA, Dussik CM, Mallick S, Dampf Stone A, Batie SF, Jacobs ET, Whitfield GK, Haussler MR, Heck MC, Jurutka PW. SIRT1 Enzymatically Potentiates 1,25-Dihydroxyvitamin D3 Signaling via Vitamin D Receptor Deacetylation. J Steroid Biochem Mol Bio. 2017 Jun 19. pii: S0960-0760(17)30161-9. doi: 10.1016/j.jsbmb.2017.06.010. [Epub ahead of print]. PMID: 28636886 PMC Journal; PMCID in progress.

Sardo-Molmenti CL, Steck SE, Hibler EA, Wang JY, Shivappa N, Yang J, Greenlee H, Wirth M, Neugut AI, Jacobs ET, Hébert JR. Dietary inflammatory index and risk of colorectal adenoma recurrence: A pooled analysis. Nutr Cancer. 2017 Feb-Mar; 69(2): 238-247. doi: 10.1080/01635581.2017.1263752. Epub 2017 Jan 17. PMID: 28094571. PMC Journal; PMCID in progress.

Languages Spoken:

English

Research Synopsis

Dr. Jacobs, is currently the Principal Investigator on a grant from the National Cancer Institute designed to study the interaction between genes and environmental risk factors related to vitamin D and its metabolism, and how they affect the risk for colorectal cancer. One of her areas of expertise and research interest is cancer prevention. Her future projects will include assessing the genetic contributors to endogenous vitamin D synthesis, and the inter-relationship between nuclear receptors as it relates to risk for cancer. Her doctoral dissertation was a thorough examination of the association between dietary fiber intake and colorectal adenoma recurrence, which since has led to collaborations with the National Cancer Institute to further explore this question.

The University of Arizona